Platelet rich plasma (PRP) is a widespread technique throughout diverse fields of Medicine for improving tissue regeneration. In dermatology, the main applications during the last years have mainly been anti-aging treatments and wound healing.
PRP contains platelets in higher concentration than whole blood and, consequently, represents a growth factor pool. Chronic wounds are characterized by a prolonged inflammatory phase, involving a continuous destruction of matrix proteins and growth factors.
Growth factors promote cell migration, proliferation and differentiation, which are essential for wound healing.
In this post, I provide you a review I have recently published including principles of PRP in wound healing and an updated critical assessment of the available clinical evidence:
The following questions are raised in the review article:
- Role of growth factors in wound healing
- PRP and its clinical application in wound healing
- Safety of PRP application in wounds
- Clinical evidence of PRP as adjunctive treatment for chronic wounds
Moreover, I suggest you a treatment algorithm that may be useful in your clinical practice. (Conde Montero E (2016) PRP in Wound Healing, In Clinical indications and treatment protocols with Platelet-rich plasma in Dermatology. Barcelona, España. Ediciones Mayo)
What is your experience with PRP in wound healing?
